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  • Title: [Propafenon-induced cholestatic liver injury--a further example for allergic drug hepatitis (author's transl)].
    Author: Schuff-Werner P, Kaiser D, Lüders CJ, Berg PA.
    Journal: Z Gastroenterol; 1981 Oct; 19(10):673-9. PubMed ID: 6117993.
    Abstract:
    In the course of cholestatic liver injury after propafenonhydrochloride medication, a high increase of the glutamatedehydrogenase up to the twenty fold of the normal range was followed by a marked raise of SGOT and SGPT. Cholestatic enzymes like gamma-glutamyl transpeptidase and alkaline phosphatase reached their maxima a week later. Within two weeks the hepatic cell enzymes and within four weeks the cholestatic enzymes have returned spontaneously to normal.
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