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  • Title: The diagnosis and management of cervical intraepithelial neoplasia in the patient under the age of twenty-one.
    Author: Dillon MB, Rosenshein NB, Parmley TH, Ruth J, Grumbine FC, Gupta PK.
    Journal: Int J Gynaecol Obstet; 1981 Apr; 19(2):97-102. PubMed ID: 6119251.
    Abstract:
    The diagnosis and management of 260 patients between the ages of 15 and 21 with cervical intraepithelial neoplasia is discussed. These patients represented 22% of all new patients seen in the Colposcopy Clinic of The Johns Hopkins Hospital between January 1975 and December 1979. Sixty-six percent of the patients were referred for evaluation of two Papanicolaou smears which were compatible with the diagnosis of CIN I while only 1.5% of the patients were referred with the cytologic diagnosis of CIN III. The colposcopic impression in the majority of patients was CIN I. There was excellent correlation between the colposcopic impression and histopathology. Thirteen percent of the patients evaluated had surgical procedures, 11% (29 patients) under-went conization and 2% (five patients) hysterectomy. The majority of patients under the age of 21 had minimal degree of cervical intraepithelial neoplasia. The importance of conservative management is discussed.
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