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  • Title: [Effect of obzidan on cerebral blood flow in acute cerebral ischemia].
    Author: Dorokhova LN.
    Journal: Farmakol Toksikol; 1982; 45(1):39-42. PubMed ID: 6120098.
    Abstract:
    The effect of obsidan on the local cerebral circulation was studied in cats with normal brain circulation and under acute cerebral ischemia. It was demonstrated that obsidan (0.2 mg/kg) increased local cerebral circulation, while on being given in a dose of 1 mg/kg it lowered it in cats with normal brain circulation. In animals with stroke (both on the side with normal circulation and on the side of cerebral ischemia) obsidan (0.2 mg/kg) significantly decreased the local cerebral circulation and destroyed autoregulation of the brain circulation.
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