These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effect of beta-receptor stimulation on the activity of the inhibitor of cAMP-dependent protein kinase.
    Author: Szmigielski A.
    Journal: Acta Physiol Pol; 1981; 32(5):501-6. PubMed ID: 6121459.
    Abstract:
    Isoprenaline and adrenaline produced an increase of cAMP content and a decrease of the activity of the endogenous inhibitor of cAMP-dependent protein kinase (type I inhibitor) in human lymphocytes and in rat heart. The maximal effect was seen at a concentration of 10(-6) M. Noradrenaline and dopamine required much higher concentration to elicite the same effect. The decrease of type I inhibitor activity was mediated through beta-adrenergic receptors because propranolol, but not phentolamine, blocked the effects produced by isoprenaline. Stimulation of beta-adrenergic receptors did not influence the activity of type II inhibitor.
    [Abstract] [Full Text] [Related] [New Search]