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Title: Biochemistry, pathophysiology and pharmacology of slow-reacting substances/leukotrienes. Author: Lewis GP. Journal: Agents Actions; 1981 Dec; 11(6-7):569-71. PubMed ID: 6122353. Abstract: The chemistry, biosynthesis and general pharmacology of leukotrienes C4 and D4 are reviewed, with emphasis on the cardiovascular and smooth muscle effects of these agents. Pathways controlling the formation of the leukotrienes are considered together with their possible pathophysiological roles.[Abstract] [Full Text] [Related] [New Search]