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  • Title: Comparative study of lorazepam and trimeprazine for oral premedication in paediatric anaesthesia.
    Author: Peters CG, Brunton JT.
    Journal: Br J Anaesth; 1982 Jun; 54(6):623-8. PubMed ID: 6123337.
    Abstract:
    One hundred and ninety-nine children received lorazepam 0.05 mg kg-1 or trimeprazine 3 mg kg-1 as oral premedication in a double-blind trial. Lorazepam proved more palatable and produced a cheerful demeanour, but possessed no significant advantages on overall assessment before surgery. Following operation, restlessness with vomiting, and evidence of retrograde amnesia occurred more frequently with lorazepam.
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