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  • Title: Sustained release aminophylline in asthma and its interaction with rimiterol.
    Author: Monie RD, Rocchiccioli KM, White JP.
    Journal: Br J Clin Pharmacol; 1982 Jul; 14(1):110-2. PubMed ID: 6125198.
    Abstract:
    Twenty chronic asthmatics who completed a double-blind cross-over study comparing sustained release aminophylline tablets with placebo had a significant improvement in airways obstruction. Inhaled rimiterol and the aminophylline tablets were shown to act in an additive manner. There was a significant reduction in asthmatic symptoms on active tablets. A further nine patients had to be withdrawn from the study because of adverse side effects.
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