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  • Title: Three-ply walled w/o/w microcapsules formed by a multiple emulsion technique.
    Author: Morris NJ, Warburton B.
    Journal: J Pharm Pharmacol; 1982 Aug; 34(8):475-9. PubMed ID: 6126555.
    Abstract:
    A new method of microencapsulation is described. Interfacial rheological studies had shown the formation of a rigid bipolymer film at the interface between an aqueous solution of a water-soluble polymer and a non-aqueous solution of an oil-soluble polymer. This led to the idea that small spherical bodies might be formed on making a w/o/w emulsion from these solutions. The present work has shown that ethyl cellulose/acacia microcapsules are formed when the organic solvent ethyl acetate is removed from the multiple emulsion drops. These microcapsules may be obtained as a free-flowing powder.
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