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  • Title: The spectrum of genitourinary abnormalities in patients with cryptorchidism, with emphasis on testicular carcinoma.
    Author: Fram RJ, Garnick MB, Retik A.
    Journal: Cancer; 1982 Nov 15; 50(10):2243-6. PubMed ID: 6127155.
    Abstract:
    A spectrum of genitourinary abnormalities occur in patients with cryptorchidism; the most important is the enhanced susceptibility to developing testis cancer. While the etiologic basis for developing testis cancer in cryptorchid patients remains controversial, failure of normal testicular development--testicular dysgenesis--may underlie carcinogenesis in the cryptorchid testis. This report reviews these associations as well as the characteristics of testis cancer in the cryptorchid testis and the evidence supporting early orchiopexy.
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