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  • Title: The adaptation of the frog tongue to various taste solutions: the effect on gustatory neural responses to bitter stimuli.
    Author: Sugimoto K, Sato T.
    Journal: Comp Biochem Physiol A Comp Physiol; 1982; 73(3):361-72. PubMed ID: 6128122.
    Abstract:
    1. After the frog tongue was adapted for 10 sec to various salts and sugars, the initial phasic component of gustatory neural responses to almost all of quinine hydrochloride (Q-HCl), quinine sulfate (Q-H2SO4). Brucine, caffeine and picric acid was suppressed. 2. Following 10 sec adaptation to acetic acid, the phasic responses to Q-HCl and Q-H2SO4 were unchanged, those to brucine and caffeine were enhanced, and that to picric acid was depressed slightly. 3. The response to any one of Q-HCl, Q-H2SO4. brucine and caffeine was suppressed after adaptation to the other three, while those to picric acid and nicotine were unchanged or enhanced after adaptation to another bitter solution.
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