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  • Title: Neuroleptic drug effect on platelet monoamine oxidase and plasma amine oxidase in schizophrenia.
    Author: Baron M, Gruen R, Levitt M, Kane J.
    Journal: Psychiatry Res; 1982 Oct; 7(2):179-87. PubMed ID: 6128754.
    Abstract:
    Activity levels of platelet monoamine oxidase (MAO) and plasma amine oxidase (PAO) were determined in eight chronic schizophrenic patients who had been treated with neuroleptic drugs for 3 months. The mean reduction in platelet MAO activity was 18.6%. The extent of decrease was statistically significant. The reduction in enzyme activity was unrelated to serum iron levels. PAO activity was unaltered. The implications for schizophrenia research are discussed.
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