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  • Title: High-dose destyrosine-gamma-endorphin in tardive dyskinesia.
    Author: Korsgaard S, Casey DE, Gerlach J.
    Journal: Psychopharmacology (Berl); 1982; 78(3):285-6. PubMed ID: 6130557.
    Abstract:
    Destyrosine-gamma-endorphin (DTGE) has purported neuroleptic properties, although the findings have been conflicting. Four chronic psychotic inpatients with neuroleptic-induced dyskinesias were treated with single injections of placebo and DTGE in high doses (20-120 mg). No consistent differences were found in tardive dyskinesia, parkinsonism, eye-blinking rates, or mental status. Laboratory tests were unchanged. It is concluded that acute DTGE treatment has no beneficial effect in drug-induced dyskinesia.
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