These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Metronidazole in prevention of cholestasis associated with total parenteral nutrition.
    Author: Capron JP, Gineston JL, Herve MA, Braillon A.
    Journal: Lancet; 1983 Feb 26; 1(8322):446-7. PubMed ID: 6131169.
    Abstract:
    The effect of metronidazole on liver function tests was studied in patients given total parenteral nutrition (TPN) for an acute attack of Crohn's disease. In those receiving TPN and metronidazole, serum activities of alkaline phosphatase and gamma-glutamyl-transferase decreased or remained normal after 30 days of TPN. In contrast, serum activities of these enzymes increased significantly after 30 days of TPN alone. These results suggest that intrahepatic cholestasis associated with TPN may be related to intestinal overgrowth of anaerobic bacteria.
    [Abstract] [Full Text] [Related] [New Search]