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  • Title: [Effect of tranquilizing agents on the blood level of endogenous ethanol in alcoholics].
    Author: Burov IuV, Treskov VG, Drozdov ES, Kovalenko AE.
    Journal: Biull Eksp Biol Med; 1983 Jan; 95(1):60-2. PubMed ID: 6131708.
    Abstract:
    Experiments on alcohol addicts blood were made to study the time course of the endogenous ethanol level after a single administration of mebicar (1.5 g), a derivative of bicyclic bisuria, 50 ml of 5% sodium hydroxybutyric syrup, a derivative of gamma-hydroxybutyric acid, and 20 mg diazepam, a derivative of 1,4-benzodiazepines. The clinical effect was recorded simultaneously. It was established that different tranquilizers stimulate the increase in the endogenous ethanol level as regards the spectrum of psychotropic activity. This effect was the most pronounced with mebicar and to a less measure with diazepam.
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