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  • Title: Synthesis and pharmacological activity of some 1-alkylamino-3-(2'-methoxy-4'-diethylcarbamoyl-phenoxy)propan-2-ols.
    Author: Monforte P, Basile M, Previtera T, Larizza A, Marmo E, De Gennaro G, Montinaro C, Filippelli W, Montanaro CS, Marfella A, Larizza D.
    Journal: Farmaco Sci; 1983 Mar; 28(3):173-86. PubMed ID: 6133779.
    Abstract:
    The synthesis and pharmacological properties of some 1-alkylamino-3-(2'-methoxy-4'-diethylcarbamoylphenoxy)propan-2-ols, related to beta-adrenergic drugs, are described. The above compounds were found to possess beta 1 and beta 2-adrenolytic activity associated with local anesthetic and antiarrhythmic activities, which are clearly inferior to those of propranolol.
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