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  • Title: Menstrual blood loss in dysmenorrhoea: effects of proquazone and indomethacin.
    Author: Mäkäräinen L, Ylikorkala O.
    Journal: Br J Obstet Gynaecol; 1983 Jun; 90(6):570-2. PubMed ID: 6134549.
    Abstract:
    Abnormal production of uterine prostaglandins (PG) causes primary dysmenorrhoea and excessive menstrual blood loss (MBL). We measured here MBL in primary dysmenorrhoea and found it to be normal during treatment with opiate analgesics (33.5 +/- 21.6 ml; mean +/- SD. n = 13), placebo (33.4 +/- 18.6 ml; n = 8), proquazone (31.8 +/- 18.0 ml; n = 8) and indomethacin (26.4 +/- 18.7 ml; n = 8). Proquazone and indomethacin relieved pain and other dysmenorrhoeic symptoms similarly in 33 women.
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