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  • Title: A case of multiple endocrine adenomatosis (Type 1) with nesidioblastosis, terminating with an exocrine pancreatic carcinoma.
    Author: Oliver MH, Drury PL, Van't Hoff W.
    Journal: Clin Endocrinol (Oxf); 1983 May; 18(5):495-403. PubMed ID: 6135520.
    Abstract:
    We describe a patient with multiple endocrine adenomatosis Type I, characterized by pituitary-dependent Cushing's Syndrome, marked hyperprolactinaemia, primary hyperparathyroidism and hyperinsulinism leading to hypoglycaemia. The patient subsequently developed an exocrine pancreatic carcinoma at the age of 32 years from which she died. An additional finding was the demonstration by immunocytochemistry of nesidioblastosis in the pancreas.
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