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  • Title: Sulphasalazine-induced systemic lupus erythematosus in a child.
    Author: Vanheule BA, Carswell F.
    Journal: Eur J Pediatr; 1983 Mar; 140(1):66-8. PubMed ID: 6135611.
    Abstract:
    A case is reported of lupus syndrome in a 13-year-old girl with ulcerative colitis treated with sulphasalazine. She had antibodies to nuclear factor and double-stranded DNA. The clinical pattern resembled drug-induced systemic lupus erythematosus and has resolved since her sulphasalazine was discontinued. Sulphasalazine-induced lupus syndrome has never been reported in a child. The history illustrates the role of sulphasalazine in the development of this syndrome.
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