These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cholinoreceptors in the corpus cavernosum muscle of the human penis.
    Author: Adaikan PG, Karim SM, Kottegoda SR, Ratnam SS.
    Journal: J Auton Pharmacol; 1983 Jun; 3(2):107-11. PubMed ID: 6136515.
    Abstract:
    Acetylcholine produced contraction, relaxation or a biphasic effect on corpus cavernosum muscle strips of human penis. These effects were antagonized by atropine but were modified by hexamethonium or tetrodotoxin suggesting the presence of excitatory and inhibitory muscarinic receptors in the human penis. Nicotine and DMPP also produced contraction or relaxation of the corpus cavernosum muscle strips. These effects were presumably indirect as they were abolished by hexamethonium and tetrodotoxin. Contractions produced by nicotine or DMPP were abolished by atropine whereas the relaxations produced by these agents were only partially blocked by atropine. Hence, the receptors mediating these relaxations are unlikely to be entirely muscarinic.
    [Abstract] [Full Text] [Related] [New Search]