These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Detection of mycobacterial antigens in cerebrospinal fluid of patients with tuberculous meningitis by enzyme-linked immunosorbent assay.
    Author: Sada E, Ruiz-Palacios GM, López-Vidal Y, Ponce de León S.
    Journal: Lancet; 1983 Sep 17; 2(8351):651-2. PubMed ID: 6136798.
    Abstract:
    Culture and identification of Mycobacterium tuberculosis in cerebrospinal fluid (CSF) of patients with tuberculous meningitis is slow, and prognosis depends on early diagnosis and treatment. An enzyme-linked immunosorbent assay with commercial BCG and anti-BCG was designed to detect mycobacterial antigens in human body fluids. Absorbance at 405 nm was measured and readings greater than or equal to 0.20 were considered positive. The readings were above 0.20 for four patients with confirmed tuberculous meningitis and nine of twelve patients with probable tuberculous meningitis. In all but one of ten patients with meningitis of other causes and in eleven control subjects the readings were below 0.20. The specificity of the test was 95% and its sensitivity 81.25%.
    [Abstract] [Full Text] [Related] [New Search]