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  • Title: Effect of gamma radiation on enzymatic activity and sulphydryl groups of human erythrocyte membrane.
    Author: Pałecz D, Leyko W.
    Journal: Int J Radiat Biol Relat Stud Phys Chem Med; 1983 Sep; 44(3):293-9. PubMed ID: 6137463.
    Abstract:
    The effect of ionizing radiation on human erythrocyte ghost membranes was studied by following changes in membrane -SH groups and activities of four membrane bound enzymes: Na+K+Mg2+ ATP-ase, Mg2+Ca2+ ATP-ase, Na+K+ATP-ase, and AChE. Irradiation up to 100 Gy gamma X-rays produced a significant decrease in the activity of ATP-ase and an increase in AChE activity. At higher radiation doses a marked decrease in the activities of all the enzymes was observed. A correlation between radiation-induced perturbations in enzyme activities and changes in membrane -SH groups was found.
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