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  • Title: [Diagnosis and treatment of Wilms' tumor].
    Author: Tsuchida Y, Saito S, Honna T, Makino S, Iwanaka T.
    Journal: Gan To Kagaku Ryoho; 1983 Oct; 10(10):2117-24. PubMed ID: 6137999.
    Abstract:
    Recent advances in the diagnosis and treatment of Wilms' tumor are reviewed. Our study disclosed that principal clinical and pathological features of Wilms' tumor are as follows: (1) It occurs in young infants and children under 5 years of age; (2) It is frequently associated with other congenital anomalies; (3) Deletion of a portion of short arm of chromosome 11 can be closely related to the tumor genesis of nephroblastoma; (4) The occurrence of distant metastases is rare at diagnosis; (5) Differential diagnosis between Wilms' tumor and neuroblastoma is occasionally quite difficult; (6) There is no good tumor marker specific to Wilms' tumor; and (7) Two-year survival rate is about 90% at present.
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