These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ethanol and GABA.
    Author: Kulonen E.
    Journal: Med Biol; 1983 Jun; 61(3):147-67. PubMed ID: 6138495.
    Abstract:
    A study of the literature showed that the GABA system is an important target of ethanol in the central nervous system, in part as a consequence of damage in membrane-bound enzymes and receptors. A single dose of ethanol initially activates the GABA system which is weakened after chronic administration because of overcompensation. Interest is focused on the GABA receptors because of the involvement of the minor tranquilizer drugs, benzodiazepines. The studies on the GABA system (metabolism, local concentrations, receptors) show great promise in the understanding and treatment of ethanol dependence and withdrawal.
    [Abstract] [Full Text] [Related] [New Search]