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  • Title: Adrenergic control of lipid metabolism.
    Author: Smith U.
    Journal: Acta Med Scand Suppl; 1983; 672():41-4. PubMed ID: 6138932.
    Abstract:
    Adrenergic receptors are ubiquitous and mediate several important effects involving lipid metabolism. Thus, beta-adrenergic stimulation increases lipolysis and inhibits the activity of the lipoprotein lipase. In contrast, alpha-adrenergic stimulation inhibits fat cell lipid mobilisation. Unexpectedly, beta-adrenergic blockade increases plasma triglyceride levels and tends to lower the high density lipoprotein (HDL-cholesterol). These effects seem to be prevented or attenuated by concomitant alpha-blockade. Possible mechanisms for the adrenergic effect on lipid metabolism are reviewed.
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