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  • Title: An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus.
    Author: Dolphin AC, Archer ER.
    Journal: Neurosci Lett; 1983 Dec 23; 43(1):49-54. PubMed ID: 6142434.
    Abstract:
    The adenosine agonist 2-chloroadenosine inhibited the K+-induced release of endogenously synthesized [3H]glutamate but not [3H]GABA from slices of rat dentate gyrus. In contrast, the K+-stimulated release of [3H]glutamate was augmented by the adenosine antagonist theophylline and was further enhanced by the cyclic AMP analogue 8-bromo-cyclic AMP in the presence of theophylline.
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