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  • Title: Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture.
    Author: Leifer D, Lipton SA, Barnstable CJ, Masland RH.
    Journal: Science; 1984 Apr 20; 224(4646):303-6. PubMed ID: 6143400.
    Abstract:
    Ganglion cells were dissociated from postnatal rat retinas, identified by specific fluorescent labels, and maintained in culture on a variety of substrates. Regeneration of processes by retinal ganglion cells was enhanced when the cells were plated on glass coated with a monoclonal antibody against the Thy-1 determinant. Plain glass and glass coated with polylysine, collagen, fibronectin, or other monoclonal antibodies supported the growth of neural processes, but were less effective than antibody to Thy-1.
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