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  • Title: The role of general practitioner research groups in the study of benzodiazepines.
    Author: Harris PG.
    Journal: Encephale; 1983; 9(4 Suppl 2):261B-265B. PubMed ID: 6144522.
    Abstract:
    The advantages of a once a day regime of a long half life benzodiazepine are illustrated by a general pratitioner study in the U.K., which showed that in a group of over 100 patients, clorazepate 15 mg nocte was equally as effective as diazepam 5 mg three times a day. Another study carried out on 50 patients randomly allocated to lorazepam 1 mg t.d.s. or to clorazepate, which was directly related to the low incidence of side effects and simplicity of dosage.
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