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  • Title: Effect of loprazolam and of triazolam on psychological functions.
    Author: Morgan K, Adam K, Oswald I.
    Journal: Psychopharmacology (Berl); 1984; 82(4):386-8. PubMed ID: 6145178.
    Abstract:
    Twelve poor sleepers of mean age 52 years performed 2 h of laboratory tests three times on 1 day during each week of nightly intake of loprazolam 0.5 mg, loprazolam 1 mg, triazolam 0.5 mg, or continued placebos. Only in the mornings did loprazolam 1 mg cause impairment in manual dexterity and card-sorting, and triazolam 0.5 mg in manual dexterity. Using difference from baseline, withdrawal of either drug after 3 weeks was associated with poorer subjective quality of sleep than following continuing placebos. The rate of spontaneous complaints (including accidents) associated with the drugs was as informative as formal testing.
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