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  • Title: Immunosuppression in new-born lambs.
    Author: Broekman J, Eksteen PA, Verwoerd DW.
    Journal: Onderstepoort J Vet Res; 1977 Sep; 44(3):151-6. PubMed ID: 614532.
    Abstract:
    A novel technique, based on cytotoxicity-neutralization, was developed for the in vitro titration of anti-sheep lymphocyte and anti-sheep macrophage sera. The titres obtained for a number of antisera were compared with those found in an agglutination assay. Anti-lymphocyte sera with a high cytotoxicity-neutralization titre very effectively suppressed the number of circulating lymphocytes in the peripheral blood of treated new-born lambs, thus indicating in vivo immunosuppressive activity.
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