These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The role of different pathways of mevalonate synthesis in the regulation of sterol and bile acid synthesis in the mammalian liver].
    Author: Poliakova ED, Denisenko TV, Dizhe EB, Klimova TA, Vasil'eva LE.
    Journal: Ukr Biokhim Zh (1978); 1984; 56(3):268-75. PubMed ID: 6147036.
    Abstract:
    The role of various pathways of synthesis are considered for mevalonic acid, the first specific precursor of sterols, in the production of cholesterol and bile acids in the mammalian liver. It is emphasized that the mevalonate synthesis with participation of acetyl-CoA-carboxylase and hydroxymethylglutaryl-CoA-reductase not bound with the endoplasmic reticulum membranes results in formation of the pool of mevalonic acid and other precursors necessary mainly for the organism supply with bile acids under conditions of cholesterol synthesis inhibition.
    [Abstract] [Full Text] [Related] [New Search]