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  • Title: Comparison of some pharmacological properties of 4-aminopyridine and 3,4-diaminopyridine in vivo.
    Author: Houston T, Pleuvry BJ.
    Journal: Br J Anaesth; 1984 Oct; 56(10):1139-42. PubMed ID: 6148094.
    Abstract:
    4-Aminopyridine and 3,4-diaminopyridine have been compared with respect to their interactions with morphine in the mouse in vivo. In contrast to 4-aminopyridine, 3,4-diaminopyridine was capable of reducing morphine-induced respiratory rate depression in doses which did not produce signs of toxicity.
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