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  • Title: [Pancreatic hormones and cyclic nucleotides in the blood in chronic recurrent pancreatitis].
    Author: Iagoda AV, Mosin VI.
    Journal: Ter Arkh; 1984; 56(12):94-6. PubMed ID: 6151752.
    Abstract:
    Patients with chronic recurrent pancreatitis were examined for the blood content of insulin, glucagon, somatostatin (SS), somatotropin (STH), cAMP and cGMP. The blood content of insulin, glucagon and STH was normal, that of SS and cAMP elevated, and that of cGMP lowered. In severe pancreatitis, the endocrine part of the pancreas was activated. The relationship was established between the level of amylasemia and the activity of islet cells and the blood content of cGMP. The compensatory importance of hypersecretion of SS and glucagon for pancreatitis exacerbation is demonstrated. The role of cyclic nucleotides in the pancreatic activity is discussed.
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