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  • Title: Inhibition of intraocular proliferations with intravitreal corticosteroids.
    Author: Tano Y, Sugita G, Abrams G, Machemer R.
    Journal: Am J Ophthalmol; 1980 Jan; 89(1):131-6. PubMed ID: 6153251.
    Abstract:
    Autotransplantation of one fourth million tissue cultured fibroblasts from rabbit rump skin into the vitreous cavity resulted in intravitreal strand formation and traction retinal detachment (27 of 47 eyes, 57%). A single intravitreal injection of 1 mg of dexamethasone alcohol inhibited fibroblast growth as judged by the significantly reduced number of retinal detachments (11 of 46 eyes, 24%). Retinal neovascularization that was observed when fibrous strands came into contact with vascularized retina (nine of 47 eyes, 19%) was also inhibited after corticosteroid application (two of 46 eyes, 4%).
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