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  • Title: [Non-A non-B hepatitis virus: demonstration of a double antigenic and structural kinship with hepatitis B virus].
    Author: Trepo C, Vitvitski L, Hantz O, Grimaud JA.
    Journal: C R Seances Acad Sci D; 1980 Jan 28; 290(4):343-6. PubMed ID: 6153582.
    Abstract:
    Major antigenic identity has been demonstrated by immunodiffusion between the Ag described by Shirachi and confirmed by us (NANB/e) in the serum on non A non B hepatitis and the HBe/3 specificity of hepatitis B virus (HBV). A second Ag (NANB/c) linked to the core of a new virion morphologically similar to HBV and also associated with ADN polymerase activity as recently described, has been identified and purified from an infected liver. This NANB/c Ag also cross reacts with HBc Ag. These results confirm that HBV and the NANB virus defined here belong to the same new class of DNA viruses.
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