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  • Title: The potential of multivariate discriminant analysis in the antenatal detection of neural tube defects.
    Author: Pettit BR, King GS, Evans S.
    Journal: Clin Chim Acta; 1980 Mar 28; 102(2-3):191-8. PubMed ID: 6154547.
    Abstract:
    A method is described which improves the ability to distinguish between normal and neural tube-defective fetuses in utero. Early second trimester amniotic fluid is classified by stepwise discriminant analysis based upon biochemical analysis for alpha-fetoprotein and eight other easily assayed variables; classification is more reliable than using alpha-fetoprotein and gestational age alone.
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