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  • Title: Intravascular coagulation and fibrinolysis syndrome (ICF) in acute non-promyelocytic leukemia.
    Author: Kotschy M, Kotlarek-Haus S, Podolak-Dawidziak M, Nowicka J, Dzik T.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1980; 107(1):65-73. PubMed ID: 6157626.
    Abstract:
    Three cases of acute non-promyelocytic leukemia complicated with intravascular coagulation and fibrinolysis syndrome were described. The blood clotting system and fibrinolysis studies in all 3 cases revealed a significant increase of FDP level and shortening of fibrinolysis time as well as a decrease of fibrinogen content in 2 cases. In one patient the recovery from ICF syndrome and complete acute leukemia remission of 8 months duration was obtained. The further 2 cases failed to improve: in one of them the ICF syndrome appeared in relapse of acute myelocytic leukemia after 2 years of its duration and in the remaining one acute undifferentiated cell leukemia of fulminating course developed in the patient suffering from bone marrow aplasia.
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