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  • Title: [Diagnosis of hemolytic anemia with unstable hemoglobin].
    Author: Sakalová A, Hrubisko M.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1980; 107(4):641-7. PubMed ID: 6162731.
    Abstract:
    Heinz-body haemolytic anaemia represents a rarely occurring kind of hereditary defect of haemoglobin, G-6-PDH or glutathion reductase. The course of disease observed in two patients with non-spherocytic haemolytic anaemia was very serious as compared with other cases with haemoglobin variants and enzyme defects of G-6-PDH described in literature. The course of disease could not be influenced by splenectomy, substitution therapy, and long-term therapy with desferrioxamin. Exitus occurred at an age 22 or 41 as a consequence of severe haemosiderosis.
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