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  • Title: [Effect of vitamin E an actinomycin D on protein and RNA synthesis in rat liver].
    Author: Palivoda OM, Donchenko GV, Metal'nikova NP.
    Journal: Ukr Biokhim Zh (1978); 1981; 53(1):67-71. PubMed ID: 6163238.
    Abstract:
    In vitro experiments showed that RNA synthesis intensity in the rat liver with E-hypovitaminosis decreases considerably while the level of the labelled precursors incorporation into protein does not differ from the norm. Under conditions of E-hypovitaminosis the inhibitory effect of actinomycin D on the RNA synthesis is pronounced more clearly as compared to the norm. In the case of the E-hypovitaminous rate liver chyme preincubation with alpha-tocopherol there is no inhibitory effect of actinomycin D on the protein biosynthesis.
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