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  • Title: Response of adrenal catecholamine to a newly synthesized chemical radioprotector.
    Author: Hasan SS, Mazumdar S, Singh PM, Pandey SN.
    Journal: Nuklearmedizin; 1981 Apr; 20(2):82-4. PubMed ID: 6165966.
    Abstract:
    This study was undertaken to try a newly synthesized compound (1-acetyl hydrazinyl thiophenyl formamidine dihydrochlorie) as a chemical radioprotector and to observe its effects on adrenal catecholamine and protein bound iodine (PBI). After whole-body irradiation, the catecholamine and serum PBI levels decreased significantly but treatment with the drug before irradiation increased the same. The whole-body irradiation resulted in a 50% mortality within a fortnight whereas the use of the drug prevented it.
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