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  • Title: [Ratio of amylase clearance and creatinine clearance in the diagnosis of acute pancreatitis].
    Author: Haffter D, Reichlin B, Gyr K.
    Journal: Schweiz Med Wochenschr; 1981 May 30; 111(22):806-8. PubMed ID: 6166043.
    Abstract:
    In 21 healthy volunteers the ratio of amylase clearance and creatinine clearance (Cam/Ccr) was determined in urine collected at admission, after a 1-hour collection period and after a 2-hour collection period. The normal values were 1.8 +/- 1.6%, 1.9 +/- 2% and 2.0 +/- 1.7% respectively. They were comparable with those published by others. The reproducibility of the method was acceptable (r = 0.62). When compared with serum amylase determinations, Cam/Ccr showed neither better sensitivity in 19 patients suffering an acute episode of proven pancreatitis, nor better specificity in 19 patients with acute abdomen but no evidence of pancreatitis.
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