These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Midodrine. A new agent in the management of idiopathic orthostatic hypotension and Shy-Drager syndrome.
    Author: Schirger A, Sheps SG, Thomas JE, Fealey RD.
    Journal: Mayo Clin Proc; 1981 Jul; 56(7):429-33. PubMed ID: 6166817.
    Abstract:
    Five patients with idiopathic orthostatic hypotension, two of whom had central nervous system manifestations (Shy-Drager syndrome), were treated with midodrine, an investigational alpha-adrenergic agonist, in a dosage of 2.5 to 5 mg three times daily. Significant improvement was observed in the standing systolic and diastolic blood pressures at the end of 1 week of therapy in all patients and has been maintained for 10 to 15 months in all patients. No symptomatic side effects were noted. Supine systolic hypertension occurred in two patients and was treated with small doses of metoprolol.
    [Abstract] [Full Text] [Related] [New Search]