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Title: Applications of synthetic oligodeoxyribonucleotides to problems in molecular biology. Author: Smith M. Journal: Nucleic Acids Symp Ser; 1980; (7):387-95. PubMed ID: 6166925. Abstract: The applications of synthetic oligodeoxyribonucleotides to problems in molecular biology described in this article are those where the oligodeoxyribonucleotide is a probe for a specific region of a nucleic acid. This includes the isolation of the iso-1-cytochrome c gene of yeast; the sequence determination of RNAs and DNAs including regions of double-stranded DNA; the introduction of defined site-specific point mutations into bacteriophage OX174 and in the in vitro selection of mutant DNA from a mixture with wild-type DNA.[Abstract] [Full Text] [Related] [New Search]