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  • Title: Prostatic-specific antigen: an immunohistologic marker for prostatic neoplasms.
    Author: Nadji M, Tabei SZ, Castro A, Chu TM, Murphy GP, Wang MC, Morales AR.
    Journal: Cancer; 1981 Sep 01; 48(5):1229-32. PubMed ID: 6168364.
    Abstract:
    Antiserum to a human prostate-specific antigen was raised in a rabbit and utilized by immunoperoxidase staining to evaluate its potential value as a diagnostic histologic marker for tumors of prostatic origin. All primary and metastatic prostatic malignancies reacted positively, whereas nonprostatic neoplasms did not stain with this procedure. This is the first immunohistochemical marker for prostate gland epithelium which does not represent prostatic acid phosphatase.
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