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  • Title: Immunolocalization of fetal aldolase isoenzymes in rat regenerating liver after carbon tetrachloride intoxication.
    Author: Le Provost E, Weber A, Schapira F, Boisnard-Rissel M, Guillouzo A.
    Journal: Oncodev Biol Med; 1980; 1(4-5):263-72. PubMed ID: 6169063.
    Abstract:
    Light and electron microscopic immunolocalization of adult and fetal aldolase isoenzymes has been studied in rat liver 72 h after CCL4 intoxication. As in rat regenerating liver after partial hepatectomy, fetal aldolases A and C were located in sinusoidal cells (Kupffer and endothelial cells) whereas adult aldolase B was present in hepatocytes only. Our results are different from those obtained with fetal and cancerous livers; they suggest that control mechanisms of gene regulation different in liver regeneration and in cancer.
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