These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Ultrastructural changes in hepatocyte nuclei reflecting genome expression and nuclear RNA biosynthesis in the early premitotic period of rat liver regeneration].
    Author: Platonov OM, Gerasimova TB, Andrianov VM, Smal'ko PIa, Korniushina TV.
    Journal: Tsitol Genet; 1981; 15(4):23-30. PubMed ID: 6169177.
    Abstract:
    Modifications of the nucleus ultrastructure and specific radioactivity of nuclear and cytoplasmic RNA from hepatocytes were studied at early stages of liver regeneration using 14C-orotic acid as a labelled precursor. It is shown that the first three hours after partial hepatectomy are characterized by mobilization of inherent abilities of the nucleus and initiation of chromatin activation. Then three hours after operation the activity of nucleolar and extranucleolar apparatus increases. By 12 hours chromatin associates with a nuclear membrane for preparing DNA replication.
    [Abstract] [Full Text] [Related] [New Search]