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  • Title: The utility of bacterial mutagenesis testing in the characterization of mobile source emissions: a review.
    Author: Claxton LD.
    Journal: Dev Toxicol Environ Sci; 1982; 10():69-82. PubMed ID: 6176436.
    Abstract:
    In summary, the work presented demonstrates that rapid, in vitro indicators of genotoxicity have been and will continue to play a valuable role in understanding the toxicity of mobile source emissions. Bacterial assays have had tremendous value in the characterization of mobile source emissions. Specifically they have had four major uses: 1) comparative screening, 2) analyzing factors that alter the genotoxicants found in emission products, 3) directing the chemical fractionation of emission organics for the identification of specific genotoxicants, and 4) analyzing the interaction of complex emission products with various mammalian systems.
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