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  • Title: Treatment of recurrent and persistent germ cell tumors with cisplatin, vinblastine, and bleomycin.
    Author: Jacobs AJ, Harris M, Deppe G, DasGupta I, Cohen CJ.
    Journal: Obstet Gynecol; 1982 Jan; 59(1):129-32. PubMed ID: 6176923.
    Abstract:
    Four patients were treated with vinblastine, cisplatin, and bleomycin for recurrent or persistent germ cell tumors. In all patients a clinical response was achieved. In 2 patients complete response was attained and they are free of disease following second-look laparotomy. One had a mixed germ cell tumor that persisted as dysgerminoma following primary chemotherapy. The other was a true hermaphrodite with pure dysgerminoma. In patients with endodermal sinus tumor transient response was achieved, but the tumors recurred and the patients died within 6 months.
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