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  • Title: Relationship of the central ACTH-immunoreactive opiocortin system to the supraoptic and paraventricular nuclei of the hypothalamus of the rat.
    Author: Knigge KM, Joseph SA.
    Journal: Brain Res; 1982 May 13; 239(2):655-8. PubMed ID: 6178471.
    Abstract:
    ACTH-immunoreactive (ir) fibers of the central opiocortin system are present in high density in the mid-portion of the paraventricular nucleus (PVN). ACTH-ir fibers, however, do not appear to directly contact oxytocin-ir vasopressin-ir, containing perikarya or axons of vasopressinergic neurons. Magnocellular neurons located more anteriorly and posteriorly in the PVN as well as those located laterally have few ACTH-ir fibers associated with them. No ACTH-ir fibers are present in the supraoptic nucleus.
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