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  • Title: [D-Penicillamine effect on collagen synthesis and structural maintenance Red Sirius staining with polarized-light examination. The value of this staining in cases of collagen diseases (author's transl)].
    Author: Pieraggi MT, Bonafe JL.
    Journal: Ann Pathol; 1982; 2(2):155-7. PubMed ID: 6179525.
    Abstract:
    A severe systemic sclerodermia has been treated by D-Penicillamine. A pathological study before and after treatment showed important changes of the collagen structure. The soluble or foetal collagen fraction is enhanced. By the Red-Sirius staining with polarized light examination of the bundles of foetal collagen are green and bright. Then, this staining appears as a marker of collagen structures.
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