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  • Title: Early studies in cybrids derived from fusion of mouse lymphosarcoma cells LS/BL and L cell cytoplasts.
    Author: Siroký J, Spurná V.
    Journal: Folia Biol (Praha); 1982; 28(3):211-22. PubMed ID: 6179803.
    Abstract:
    This paper describes the proliferative and morphological properties of cybrid cells derived from fusion of the whole cells of a mouse lymphosarcoma LS/BL and cytoplasts prepared from L cells or their biochemically marked mutants (HGPRT-). In cybrids, decondensation of parent LS/BL nuclei and their cooperation with heterologous cytoplasm was observed. Cybrids incorporated the precursors of nucleic acid and protein synthesis up to 70 h after fusion.
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